Stephanie and her mom Darcy lost a combined weight of 320 lbs.; BJ overcame drug and food addiction to lose 350 lbs. and his body is now covered with excess skin.
Antonia overcame her food addiction to lose 190lbs, but the extra skin is keeping her from feeling confident and sexy; Natasha lost almost 300lbs after gastric bypass surgery, but now struggles with carrying a lot of saggy excess skin.
Linda is hoping skin removal surgery will give her the self-esteem she needs to be an amazing role model to her daughters; Angel hates her extra skin because it's turning her into an introvert around her family.
Shantel needs to get rid of her excess skin to gain the confidence she needs to set a positive example for her daughter; Hope has an obsession with weight loss that could make her too unhealthy to have skin removal surgery.
After losing 275 lbs., Mikki became a fitness fanatic, but the weight loss left her with a lot of sagging skin; Denise's obesity always made her feel invisible, but after losing 200 lbs. the skin still hinders her from fitting in with her family.
Rebecca lost her weight to be more active with her young son, but the plan backfired because she's now trapped in her excess skin; after his dad died, Sal dropped a ton of weight, but with all the excess skin, he fears he will never become a dad.
Autumn wants to make up for lost time with her son, but the excess skin from major weight loss is holding her back; Cody always pretended to be happy when he was 500-lbs, but after losing the weight, he's covered in skin and is sick of pretending.
Ronnie and Michael Robinette are thriving, but their extra skin is getting in the way; at 64, Renee's excess skin inhibits her from enjoying her relationship and expressing her true self in public.
Tamika finds a partner who makes her feel happy, but she feels uncomfortable due to her excess skin; Emilly blames herself for her son's weight gain, and, now, they both struggle with the pain loose skin has brought into their lives.
After being a victim of a crime, Marranda finds solace in food and her weight balloons; she loses the weight, but her skin is a reminder of her trauma; Jannet's excess skin is keeping her from meeting a life partner.
Rafael loses over 500 pounds through diet and exercise, but his excess skin becomes a huge hindrance on his life and progress; Anna loses 330 pounds but her low self-esteem holds her back from being the mother she wants to be.
Carlynda needs two full knee replacements but doctors won't perform surgery until the skin is gone; after extreme weight loss and marrying the love of her life, Karen wants to start a family, but her excess skin gets in her way.
Julie's globs of excess skin cause her to recoil from the touch of her children; Andrew shed 300-lbs. by spending every spare moment in the gym, but is now engulfed in empty skin that's killing his dream of body-building.
Megan lost weight after being bullied in high school but is still constantly tormented when she sees her dramatic loose skin in the mirror; Ashley lost 220-lbs. but her excess skin that leaves her in pain.
Holly lost 200 pounds after a life of abuse, but now excess skin keeps her from the wedding of her dreams; a health scare could affect Mark's upcoming skin removal surgery.
Brenda's excess skin forces an end to her marriage; Mellisa's 180-pound weight loss leaves her with loose skin that affects her relationship with her daughters.
After her husband suddenly passes away, Jenae reaches 512 pounds, but her excess skin hides her weight loss; Julie's excess skin provides a constant reminder of her obesity and how it damaged her marriage.
Sarah turned to food for comfort during her damaging childhood, but her weight loss left her with sagging skin; Roger overcame a challenging life to raise his children, but his weight loss gave him restricting excess skin.
Annette lost over half of her body weight, but her excess skin is a painful reminder of years of overeating; Callisto lost 250 pounds and became a model, but the shame of her loose skin put her passion and marriage on hold.
Sisters Jessica and Melissa are left with massive excess hanging skin after growing up morbidly obese; Matt lost everything he cherished, but after losing weight, his excess skin keeps him from returning to life.
Megan feels physically and mentally trapped with excess skin under her clothes; Yalena's extreme weight loss counts for nothing unless she sheds her excess skin.
Melissa lost 235 pounds, but her confidence is still low because of her excess skin; Jeff has lost 300 pounds, but continues to hide himself from the world.
Lindsey lost 140 pounds, but her sagging skin keeps her athletic dreams out of reach; Derek wants to pass the Police Academy physical but his excess skin prevents him from training.
Ariel is 23 and has already lost 260 pounds, but finds the excess skin less feminine than being obese; spirited Chantae is desperate to enjoy life again after losing 222 pounds.