Amy's past comes back to haunt her when a desperate father sacrifices everything to secure his daughter's heart transplant.
Amy grapples with having memories while treating a mother-to-be with a mysterious condition; Dr. Joan Ridley, Amy's mentor, visits Westside.
A patient forces Amy to confront the realities of medical tourism; TJ helps a veteran with his prosthetic; Joan drops a bombshell.
An outdated medical proxy form creates tension between a patient's ex-husband and current partner; Amy, Jake and new intern Hannah investigate a college student's sudden blindness.
A popular weight loss medication reveals the cracks in a couple's relationship; two sisters face an unexpected diagnosis.
Amy treats a chaplain who helps her reconcile with the past; Michael is under investigation for his actions during the hostage crisis; TJ returns to work and treats a prisoner; Hannah's brother shows up with a plan.
Amy and Gina, with an assist from Jake, team up to help a victim of domestic abuse; TJ finds himself in the spotlight when he, Sonya and Liz treat a social media influencer; Hannah and Charlie conspire to destroy Amy.
After receiving tragic news, Jake refuses to give up on a beloved patient, landing himself in conflict with several Westside surgeons; when Amy's neuro tests elicit memories of Danny, she pushes herself too far.
At Jake's father's funeral, grief helps clarify his feelings for Amy; in a gripping flashback story, Jake's past intentions to leave Westside are revealed, along with the reason he decided to stay; Charlie goes too far with the plan to destroy Amy.
With the search underway to find out the truth about Amy's hacked accounts, she and Sonya butt heads while treating a homeless patient; Jake and TJ help a distraught mother figure out why her daughter is in a coma.
The search for Amy's hacker intensifies when the hospital finally brings in the FBI; Hannah, devastated by the death of her patient, works with Amy to treat a sick older man whose daughter believes has been poisoned.
Charlie fights for his life at Westside with Hannah by his side; a familiar face returns to Westside and Amy is not happy about it.
The race for chief resident intensifies as Joan tasks Amy and Sonya with evaluating each other's case work; Amy tends to a politician with a disability whose dire health complications threaten to interrupt a crucial vote.