Dwyane Wade returns with guests Gabrielle Union-Wade and La La Anthony to take on new games for charity.
Gabrielle Union-Wade and Lala Anthony might make Cube history; Kweku and Kofi, having seen the Cube destroy many teams last season, are here to avenge the plexiglass they call "Little Cubie."
Welcoming nurses Natasha and Kiana, who are confident they will conquer the Cube with their sporting background and surgical hands.
Wanda Dench shot to viral fame when she accidentally texted stranger Jamal Hinton in error when she intended to invite her grandson over for Thanksgiving; six years on, they hope to be thankful for a $250,000 windfall.
The Cube is faced with a competitor like no other as NBA legend Shaquille O'Neal takes on the Cube in a solo attempt to win money for charity.
The Cube might have met his match when Baltimore BFFs Brianna and Niyah show the Cube a thing or two about attitude.
Best friends and fellow teachers John and Dave set out to teach the Cube a lesson.
Cheer coaches Tommy and Jermaine tumble into The Cube bursting with positivity.
Two brothers from San Francisco, Brian and Branden, continue their game with their eyes on the 250k prize.
Youth ministers and married couple Larissa and Luis take on the Cube.
Texas Cowboy's Ben Senior and Ben Junior are out to tame The Cube and bag themselves a quarter of a million dollars.
Dwyane Wade introduces the cube.
Host Dwyane Wade steps back into the arena to help husband-and-wife team Kal and Whitney beat The Cube for a chance to win $250,000.
The games get harder as the prize money increases for married couple Daisy and Taylor; host Dwyane Wade uses an assist to give friends Stephen and Chris a One-Shot as they set out to beat The Cube.
Siblings Kelsey and Jared face the challenges of "The Cube."
The pressure is mounting as two new teams enter the Cube for another chance at winning $250,000; with nine lives and seven games, it's time to figure out who has what it takes.
Lovebirds Elie and Keyana are fierce competitors and are on the verge of making Cube history; meet engineers Jenni and Marie as they use science in their attempts to beat the Cube.
They came to beat the The Cube with their scientific superpowers, but will engineers Jenni and Marie finish with a Big Bang? Next up, best friends Audrey and Kavi are determined that The Cube is no match for their positive energy and unbreakable bon.
Will, Audrey and Kavi; Brian and Chanel.
Mother and daughter duo Shanden and Mae and best friend teachers Sammy and Lucson compete.
Dynamic duo Sammy and Lucson attempt to go far; champion ax-throwing sisters Ellie and Anna try to take the Cube's money; Dwyane Wade is called off the bench for one final time to take the One-Shot.