Known as the founder of the notorious Chicago street gang, the Gangster Disciples, Hoover starts one of the first street gangs that was run as a business; while in state prison, Hoover runs a $100 million-a-year drug business.
By the time Perrion is in her 20s, she becomes a drug queenpin, with ties to Mexican drug cartels; in the present day, Perrion's drug trafficking charges are dropped and she now works as a political adviser and fights for prisoners' rights.
Shauntay Henderson was one of the handful of women to appear on the FBI's Most Wanted List; known on the streets as Two Guns, her penchant for fist fighting and high-speed police chases helped contribute to her status as a violent criminal.
A Mexican drug lord and former leader of the Sinaloa cartel, considered by many as one of the most powerful drug traffickers in the world, receives the title of biggest drug lord of all time; the DEA considers him the godfather of the drug world.
Dawud Cool Bey is known as the Philly Intimidator, and he was a key player in the hierarchy in the Kaboni Savage Organization, a drug-trafficking gang led by Kaboni Savage; it is alleged that Bey plotted to kill witnesses; Bey was arrested in 2004.
Young Boys Incorporated was a drug-trafficking gang founded in Detroit in the late '70s, and Milton Butch Jones, Raymond Peoples, and Dwayne Davis rose up the ranks and ran the organization; it was considered innovative because it employed teenagers.
Scarfo rose to power during one of the bloodiest periods in Philadelphia organized crime history; more than two dozen mob members or associates were murdered between 1980 and 1985 as Scarfo took control of the Philadelphia mob.
Sam Giancana was a top mob boss; he started out as a driver for Al Capone, and by the Great Depression, Giancana was building his own reputation; Giancana is connected to conspiracy theories involving both the Kennedy family and Fidel Castro.
Spilotro was a soldier for the Chicago Outfit and was assigned to protect the Las Vegas skim: the illegal diversion of casino profits to the Mob; Spilotro's violent extracurricular activities hastened the demise of the Mob's influence in Las Vegas.
Chester Campbell is one of the most notorious figures in Detroit and within the world of organized crime; he served two brief stretches in prison, but he is believed to be connected to more than a dozen murders.
In the Hollywood of the 1970s and '80s, Eddie Nash was a nightclub impresario who used drug trafficking to build a fortune; with ties to the mafia, Nash owned dozens of restaurants.
The '80s are remembered for big hair and neon lights; another popular staple of the decade was cocaine.
Cabrera's criminal history dates back to his youth in the Santa Cruz, Calif., area.
Clarence Heatley and his Preacher Crew; the crew extorted, kidnapped, and even killed to gain notoriety on the streets of the Bronx and Harlem.
Moya and his chief enforcer, Andre Paige, led a deadly narcotics and extortion racket in New York City.
Lisette Lee, the supposed Samsung heiress who lived a mysterious life of privilege and luxury until her arrest for narcotics trafficking in 2010.
Federal agents say Doc's aim was to take on the Hells Angels and run a massive criminal enterprise engaged in drug running, murder and intimidation.
With a taste of success and the lure of easy money, Thelma started transporting cocaine and heroin between Los Angeles and Philadelphia.
Carlos Lehder uses the Bahamian island of Norman's Cay as a headquarters as he smuggles cocaine from Colombia to the United States.
Christopher Coke used his criminal wealth and prosperity to win the hearts of his community and influence their political affiliations.
Barry Mills found his calling as the leader of the white supremacist prison gang the Aryan Brotherhood.
Maria Leon commanded a reign of terror in L.A.; the criminal underworld created by her murderous brood of children.
Pistol Pete and his underlings incorporated the gang Sex, Money, Murder in an effort to launder drug money and expanded their operations outside New York.
A pair of powerboat racers who allegedly moved more illegal narcotics than just about anyone in the history of the U.S. War on Drugs.
The Cutt Boyz use violence to control the drug trade within the B.W. Cooper Housing Complex in New Orleans.
Bostic's New Breeds would package and distribute heroin and defend their turf with violence.
Quasand Lewis made millions by way of drug trafficking; the federal government launched "Operation Falling Star" in order to take down 'Q' and build the largest drug related prosecution in the history of the state of Michigan.
Bowman, as international president of the Outlaws Motorcycle Club, ordered kidnappings, fire bombings, assaults and murders.
Griselda Blanco is suspected of scores of murders while transporting cocaine from Colombia to the United States.
The rise and fall of Albert "Alpo" Martinez, dubbed the "Mayor of Harlem."
Johnny Eng, one of the most notorious drug traffickers in the history of Manhattan's Chinatown.
From a prison cell, Felipe founded the New York chapter of the Latin Kings street gang; Felipe's own writings would incriminate him.
Anthony Shea, one of the most prolific bank and armored truck robbers.
Thompson rose to the top of the cocaine trade; she was released from prison in 2005 and is now an evangelical minister.
Garcia was the head of a deadly heroin ring in the Bronx; Henao led an ecstasy drug ring out of the Netherlands; Sandra Avila Beltran was a Mexican drug cartel leader.