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While trying to learn which marriage and fertility superstitions lead to a happy life, George discovers what might have gone wrong with his own failed marriage.
To learn about food superstitions and their origins, George takes to the high seas, confronts alligators, and has an experience he never expected when he agrees to hunt for his dinner in the backwoods of Missouri.
In trying to reveal the difference between religion and superstition, George uncovers some of life's great secrets.
George visits the Las Vegas Strip and Wall Street to learn if lucky charms and strange rituals can actually help fatten one's wallet.
George tries to communicate with a recently departed friend to learn if there are invisible souls, spirits, or life after death.
George goes head-to-head with professional boxers, baseball stars and football fanatics to try to uncover the truth behind some of sports' greatest superstitions.
George meets several people who believe they are truly cursed, and takes them to a psychic, a voodoo priestess and a holistic healer to see if any superstitions can break the spells.
George travels from the swamps of Louisiana to the backstage corridors of Broadway to find out what superstitions people use to ward off evil spirits, and if any of them actually work.
George gets personal as he shares his favorite superstitious adventures, from the craziest ones that made him laugh to those that changed him forever.