Villanelle is a psychopathic assassin, and Eve is the woman charged with hunting her down; the two fiercely intelligent women, equally obsessed with each other, go head to head in an epic game of cat and mouse.
Eve is on a revenge mission against The Twelve; she has a lead and needs to track her down via one of her assassins; Villanelle wants to change, so she endears herself to a church community; Carolyn is focused on getting back in the game.
Eve locates Helene, who may be useful in her revenge mission against The Twelve; Villanelle's quest for change goes awry. Carolyn is pushed aside by MI6 and is forced to seek cooperation elsewhere -- she needs to find out who ordered Kenny's hit.
Having stalked Helene, a new lead allows Eve to uncover a name in The Twelve's top tier; Villanelle is rejected by Eve when she seeks help; operating abroad, Carolyn discovers more promising intel on a spate of torturous murders linked to The Twelve.
Eve struggles to identify her lead in The Twelve; Villanelle gets her mojo back -- she decides to be good by embracing what she's good at: killing; Carolyn discovers an old acquaintance in Cuba and decides to go rogue.
Eve and Villanelle reunite before parting to pursue their own missions, which leads Villanelle to another assassin in The Twelve; Eve moves closer to achieving her revenge mission; Carolyn is forced to face a ghost from her past.
Eve takes on an even bigger revenge mission against The Twelve and realizes she may need Villanelle's help; Villanelle has a dalliance with the new assassin; Carolyn's latest string of intel may lead her home.
Eve and Villanelle focus on making a seismic stab at The Twelve, risking their own lives; Carolyn arrives home as a traitor, she has a finite amount of time to use her intel as leverage to get herself back in the game.
After being shot by Villanelle, Eve is attempting to rebuild her life; Villanelle is also moving on, until she is approached by an old foe; Carolyn is being undermined at work and Kenny can't leave his own investigation into The Twelve alone.
Eve and Carolyn are reeling; Eve strikes up an unlikely alliance with Kenny's colleagues at the Bitter Pill; Villanelle finds that management isn't all it's cracked up to be.
Eve is trying to patch up things with Niko; Villanelle receives good news about her upcoming promotion but can't shake the feeling there's still something missing from her life; Dasha seeks a solution to Villanelle's erratic behavior.
Villanelle returns home to Mother Russia to try to find her family; perhaps a new connection to her roots will give her back what's been missing in her life.
Carolyn finds out information is being withheld by those close to her; Eve finds a lead on Villanelle; meanwhile, Villanelle has had enough and decides on a different path; Konstantin's loyalties are split.
Carolyn is frustrated with the lack of progress in the investigation; Eve is focused on Villanelle and finds a clue to her whereabouts; Villanelle and Dasha work together on a kill; the pressure is getting to Konstantin.
Konstantin makes a break for it; Carolyn might have finally found what she's looking for; Eve and Villanelle try to work out what the future may hold for them, together or apart.
Eve is reeling from her act of violence against Villanelle and doesn't know whether she is alive or dead; a paranoid and severely injured Villanelle manages to get herself to the hospital for treatment; Carolyn approaches Eve with an opportunity.
Carolyn introduces Eve to her new team before Eve briefs them on the Villanelle case; Villanelle, needing to lie low while she recovers, finds a good Samaritan to take her in and care for her; Eve finds out a secret that Carolyn has been hiding.
Villanelle decides to take matters into her own hands on a trip to Amsterdam; Carolyn is called in to face the music with her boss; after the discovery of another dead body, Eve and her new team make a break in their case.
The MI6 team make a pact with the devil in order to get information from The Ghost; a visitor from Broadmoor comes with a dire warning; Eve and Villanelle find themselves closer than ever.
Villanelle uses her unrivaled infiltration skills to immerse herself in the world of a new target; their relationship on the rocks, Eve and Niko confront each other about their future.
Villanelle dives deep into the dangerous world of her target under the guise of her newfound persona, Billie; Eve may have worrying competition for Villanelle's affections.
Eve's mission is disastrously compromised; Carolyn briefs Eve on her current status as an employee of the British government and leaves Eve's future in her own hands; Villanelle does everything she can in order to get to her ultimate target.
In the aftermath of her recent assignment, Villanelle is ordered to take a break; never one to do as she's told, she goes ahead with her next mission regardless; Eve is given a dream opportunity to join a secret MI6 unit tracking Villanelle.
When Villanelle kills a Chinese colonel at a kink clinic in Berlin, Eve and Bill travel to investigate; while Eve and Bill chase up a number of promising leads, Villanelle enjoys the cat-and-mouse of their proximity.
Intel from Berlin points to the existence of a mole, prompting Eve to undertake her first surveillance operation; Villanelle is sent to England to eliminate a member of British Intelligence.
Having survived a terrifying close call with Villanelle, Eve now has the mole ensconced in a safe house and is buzzing; they have an exciting opportunity to glean information and crack this thing open.
Eve and Carolyn head out to Moscow to negotiate access to a female assassin that could hold the key to the organization that runs Villanelle; Villanelle is smuggled into the same Russian jail.
Tensions run high as the situation in Moscow escalates; Eve starts to question who she can trust; despite the danger, with her sights firmly set on Villanelle, Eve goes rogue; with both women under pressure, the stakes are higher than ever.