Daniel Simon and Dr. Mike search for Sully, who is dying in the wilderness from injuries suffered when he fled the Cavalry.
Dr. Mike (Jane Seymour) keeps Sully's (Joe Lando) whereabouts a secret as she tries to help him recover from his wounds. With John Schneider and David Beecroft.
Hank, believing Sully and Cloud Dancing to be the instigators of the American Indian raids, declares himself sheriff and sets off to capture them.
Dr. Mike is shocked when a Russian princess convinces the townsfolk she is a seer with ties to the spirit world.
Grace and Robert E.'s adopted son may not survive; fugitive Sully works for peace and learns of Mike's miscarriage.
Mike's sister Marjorie is a temperance crusader; Sully and Cloud Dancing try reasoning with Black Moon.
Mike sends the children to Sully's hideout, but her visiting family refuses to leave diphtheria-ravaged Colorado Springs.
Dr. Mike tries to protect her family from a diphtheria epidemic, but her mother and two sisters refuse to leave town.
Matthew's legal studies lead to a flurry of lawsuits after Horace seeks restitution from Hank for accidentally breaking his nose.
An Indian-hater determines to thwart a treaty that would allow Black Cloud's warriors safe passage and let Sully come home.
Returning from the reservation, Dr. Mike and Sully hope to make it home for Christmas, but are waylaid when they help a young couple lost in the wilderness.
Sully and the townsfolk worry about Dr. Mike when she begins having recurring nightmares after being shot by a man with a hatred of doctors.
Dr. Mike's dislike of Colleen's charming but rather aggressive boyfriend is validated when Andrew has to protect Colleen from abuse.
Dr. Mike tries to prevent grief-stricken Loren from moving away; the town prepares for the "Sweethearts Dance."
Dr. Quinn (Jane Seymour) befriends a young Chinese woman (Yumi Iwama) who must pretend to be a man so she can practice medicine.
Teresa's aunt tries to stop her from marrying Jake; Dorothy wants to free Cloud Dancing and run away with him.
Dr. Mike learns that a strange but seemingly harmless man whom Brian has befriended is actually an escapee from an insane asylum.
Matthew (Chad Allen) defends lawman Elias Burch (guest star Willie Nelson) against charges that he murdered an unarmed ex-con. With Jane Seymour.
Mike and Sully reminisce about ups and downs of their relationship when a head injury forces Mike to stay awake or risk a coma.
After the death of his son and the breakup of his marriage, furious Robert E. fights a visiting boxing champion.
Medical student Colleen accepts Andrew's proposal; Preston offers to buy Jake's share of the Golden Nugget.
Robbers wreck a train carrying Sully and Cloud Dancing; Andrew is reluctant to return the practice to Dr. Mike.
Dr. Mike finds the stresses of being a wife, mother and career woman too much and contemplates turning her practice over to Dr. Cook.
A malpractice suit prevents Dr. Mike from practicing medicine, leaving the reluctant Dr. Cook in charge.
The appearance of renowned singer Gilda St. Clair tempts Colleen to leave college and travel the world instead.
A Latin American woman rebuffs Dr. Mike's attempts at friendship; the Rev. Johnson searches for a teacher to take his place.
Sully gets an offer to survey the newly created Yellowstone National Park; Brian's first date; Dorothy teaches Cloud Dancing ballroom steps.
Jake and Preston each want Mike's mayoral endorsement, until she is jailed for treating a fugitive Indian.
A sick and ragged prospector wanders into town, and Jake Slicker recognizes the man as his father, who abandoned him years before.
Dr. Mike, Sully and Matthew team up with a legendary marshal in order to nab the thieves who wounded Matthew during a bank robbery.
A severe storm bears down on Colorado Springs, disrupting the arrival of Preston Lodge II and Dr. Mike's attempts to prepare a Thanksgiving dinner.
Robert E. and Brian try to enroll Anthony in the all-white school; Jake and Hank open a hotel to rival Preston's.
Dr. Mike's practice is in jeopardy when her patients begin dying of a mysterious infection apparently contracted at the clinic.
As Christmas approaches, Brian questions his faith when he learns that Dr. Mike cannot save the Rev. Johnson's sight.
In a case of mistaken motivation, a judge sends Sully to prison after he is spotted with criminals bent on stopping the construction of a dam.
Dr. Mike's Uncle Theodore, a concert pianist, sees in Brian not only a talented musician, but his own dead son.
Kid Cole and Sister Ruth (Johnny Cash, June Carter Cash) visit Dr. Mike (Jane Seymour) at a difficult time in their marriage.
Dr. Mike and Colleen recall past cases as part of a college course Colleen is taking; Andrew is overcome by a mysterious ailment.
An old friend of Sully's seeks an affair with Dr. Mike while flashing his financial success before the family.
Despite being wounded by two bank robbers, Sully works to free his wife, Brian and Katie when they are taken hostage by the desperate men.
Brian takes a liking to visiting writer Walt Whitman, even when the townspeople shun Whitman over rumors of his alternative lifestyle.
Horace attempts suicide after his wife leaves him, prompting Dr. Mike to send for her and their young daughter.
Dr. Mike is shocked by her sister's liberal behavior and open relationship with Loren Bray after she joins the women's suffrage movement.
When Brian's irresponsible behavior puts the town in danger, Sully must step in and begin acting like a real father to the boy.
When Sgt. McKay holds Sully responsible for the Dog Soldiers' attacks, he and Cloud Dancing escape to safer American Indian lands.
Dr. Mike and Sully's return from their honeymoon is marred by the arrival of a greedy banker and Cloud Dancing's hatred of the reservation.
Baseball fever hits town when an all-star team arrives; the townspeople agree to split profits from a match with the traveling challengers.
Mike becomes more absorbed in her new role as wife; rebellious Colleen joins schoolmates for dangerous and questionable escapades.
Matthew's fiancee, Ingrid, is making final wedding plans when she is attacked by Brian's rabid dog and becomes gravely ill.
Though an elderly patient believes the springs are helping him, Dr. Mike knows his improvements are psychological; Mike wants Sully to play Prince Charming.
Dorothy Jennings' book about her experiences in Colorado Springs becomes a best seller, but it angers townsfolk.
Loren proposes to Dorothy but has a stroke before she can answer; an old friend wants Sully to come to the gold fields.
Dr. Mike celebrates her birthday by climbing Pikes Peak with Dorothy, Grace and Myra but ends up injured and alone.
Dr. Mike fears she is unable to have a child because of her age; the townspeople debate sharing their feast with the Cheyenne on the reservation.
Dr. Mike (Jane Seymour) finds a heartbroken and self-destructive Matthew (Chad Allen) courting danger in a plague-ridden town.
Dr. Mike gets a mischievous poodle; Brian is smitten with a new girl in town; the Rev. Johnson recruits folk for a Nativity pageant.
Robert E wants to adopt a sick boy, but Grace is hesitant about becoming attached; Dr. Mike struggles to diagnose the child.
Matthew's grief finally gives way to a new romance, but his heart goes to a woman working for Hank in the brothel.
During Dr. Mike's (Jane Seymour) absence, the residents of Colorado Springs become prey to a con man. With Joe Lando and Orson Bean.
Sully leads the rescue when a boy is kidnapped by a mountain man; Dr. Mike's pregnancy is in danger when she does not take care of herself.
Sully leaves the unruly rescue party to hunt for Matthew on his own; Dr. Mike's least favorite physician takes over her practice.
When the Rev. Johnson finds his former mentor plans a visit, he borrows money from Hank to fix up his ramshackle church.
Capital punishment divides Colorado Springs when a man convicted of rape and murder is sentenced to die.
Cloud Dancing sees a reservation school as fatal to Indian culture; bankers stonewall Dorothy's loan request.
Dr. Mike's joyful reunion with a college friend soon turns competitive; Dorothy struggles with a new press.
After being nominated for Colorado's Woman of the Year, Dr. Mike finds it nearly impossible to live up to everyone's expectations.
A renegade stabs Cloud Dancing, and Emma has a tumor, so Mike cannot slow down before the baby is born.
The residents of Colorado Springs welcome an artist until they discover she carries a disease, causing Dr. Mike to face her own fears.
Cloud Dancing claims responsibility when a young soldier is inadvertently shot during a fight between the Army and the American Indians.
Dr. Mike prepares for the birth of her baby; Sully is hurt while trying to rescue Cloud Dancing and others from Sgt. O'Connor and his patrol.
Cloud Dancing leads pregnant Dr. Mike through the wilderness to Sully; Dr. Cook is forced to perform a major operation.
Loren plans a trip to Bolivia to prove he is not getting old; Brian seeks to prove his courage by camping out alone.
Matthew inherits a herd of cattle after Olive dies, and the townspeople help him drive the herd to Colorado Springs.
Matthew's attempts to prove himself as a trail boss lead to the loss of cattle and a near loss of life.
Mike donates her father's book collection to start the town library, touching off a furor over censorship.
Dr. Mike (Jane Seymour) performs experimental reconstructive surgery on a disfigured man (Richard Moll). With Joe Lando and Chad Allen.
Sully is imprisoned for army desertion, after uncovering an assassination plot, Dr. Mike sends the children home.
Mike's offer to pay for supplies needed to finish the new house threatens Sully's pride; Myra and Horace consult Mike about Myra's sleepwalking.
Mike feels responsible for friends who were robbed on the Denver stagecoach; the kids prepare Thanksgiving dinner.
Dorothy ignores Mike's advice after finding a lump in her breast; maturing Colleen endures ridicule from boys.
Dorothy insists the decision to have surgery is hers, not Mike's; Colleen finds the harassment unbearable.
The town's Christmas spirit is in question when a Jewish immigrant family arrives in Colorado Springs.
Appointed by the government to represent Indian rights, Sully learns his supervisor is selling goods intended for the Cheyenne to local merchants.
The townspeople spend what they believe will be their last days on Earth in a state of panic after a newspaper reports that a deadly comet is coming.
Mike meets a kindred soul in an older woman who comes to climb Pikes Peak; Grace deals with her jealousy of Myra's pregnancy.
Ethan Cooper returns to Colorado Springs with his new wife to give his blessing on Michaela and Sully's planned adoption.
Mike's faith in Robert E. leads her to recommend him for the dangerous job of repairing a steam engine.
After the visiting Belle Starr gets into a bar fight, she stays with Dr. Mike and disrupts her peaceful home life.
Dr. Mike and Sully try to stop a paleontologist who is digging up Cheyenne burial sites while searching for dinosaur bones.
Substitute instructor Mike gets in trouble for teaching evolution theory; Mike takes an abused girl under her wing.
Mike and Sully arrive too late to avert Custer's slaughter of the Indians at the Washita River; Brian befriends an Indian boy.
Sully must overcome his spiritual crisis in order to save Loren, who has been critically injured in the wilderness.
Dr. Mike and Sully remember the events that have marked their love affair and have second thoughts about their impending nuptials.
Sully returns; Mike realizes she wants to marry Sully; Brian has a surprise for the newlyweds.
Mike and Sully are ready to tie the knot, but not before they tie up some loose ends. Part 1 of two.
Rules forbid Mike from entering her horse in an important race; Brian faces discrimination in a cooking contest.
Dr. Mike must use medical evidence to prove Loren's sister-in-law did not murder her abusive husband.
On Halloween, the residents of Colorado Springs are frightened by a mysterious dead man who keeps appearing and disappearing all over town.
When Jake is accused of killing a Cheyenne, the divided town depends on Sully's peacemaking ability to avoid retribution.
Dr. Mike clashes with a faith healer over the necessity of Kid Cole's treatment; Robert E and Grace encounter problems when they plan to marry.
When Colorado Springs is hit by a severe drought, Jake and Loren put the townspeople in danger by stealing water from the Cheyenne.
On the eve of the Sweethearts Dance, Mike sees Sully with Dorothy, and Colleen is accused of stealing a friend's boyfriend.
When a misunderstanding leads the cavalry to place a bounty on Sully, Matthew, Colleen and Brian hide their injured friend.
While caring for a pregnant woman on Christmas Eve, Dr. Mike is visited by the spirit of Charlotte Cooper.
A cave-in traps Matthew, bringing Sully to the rescue; Loren refuses credit to strikers, prompting a boycott of his store.
Mike feels responsible for typhus transmitted to the Cheyenne through government-issued blankets she urged them to accept.
When a woman brings her traveling circus to Colorado Springs, both Matthew and Dr. Mike try to help her self-conscious daughter.
Mike's patient, a woman wounded during a massacre, falls for Sully; Loren thinks Dorothy is seeing more of Jake than him.
Matthew, Colleen and Brian feel neglected when Dr. Mike and the Rev. Johnson search for families that will adopt orphans.
Sully and Michaela scout for information that will prevent further bloodshed when the Buffalo Soldiers arrive to confront renegade Indians.
Dr. Mike and Sully try to dissuade Matthew when a slick card shark teaches him to gamble and he believes he's found an easy way to make money.
Dr. Mike clashes with Dorothy when she acts to protect her family from her friend's desperate son, who is addicted to morphine.
A Denver banker brings the Ku Klux Klan to Colorado Springs to find new members and force Robert E to leave his home.
Mike suspects the new teacher, a good friend, abuses students; the Rev. Johnson is torn by feelings for the woman.
While visiting the Indian reservation, Mike and Sully see renegade Dog Soldiers shoot some Cavalry men; Mike is kidnapped; Brian falls in love with a horse that Hank wins in a poker game.
Mike's mayoral candidacy sparks a debate on women's rights; Myra is assaulted by a customer Hank wanted her to entertain.
When Myra finally leaves the business, Hank flies into a drunken rage and shoots up the town, ending up in a coma under Dr. Mike's care.
The fiancé whom Mike had presumed was killed in the Civil War shows up in Colorado Springs.
While trying to stave off an influenza epidemic, Dr. Mike falls prey to the deadly virus, leaving the town in jeopardy.
Dr. Mike's disapproving mother visits from Boston and finds her daughter's unconventional life on the frontier difficult to accept.
Dr. Mike hires a retired gunslinger as sheriff to save the life of an orphaned immigrant who stole a cow to feed his starving family.
A bitter Loren, who blames Sully for his daughter's death, tries to repossess Dr. Mike's cabin when he learns he still owns the deed.
Dr. Mike is suspicious when Charlotte's husband returns to the children he abandoned and tries to convince the town that he has changed.
Dr. Mike threatens a wealthy mining baron when mercury from his mine contaminates the town's water supply and causes illness in the community.
When a medicine-show man arrives in town, selling an elixir he claims will cure anything, Dr. Mike becomes determined to prove him a fraud.
A thieving cowhand rides into town and quickly disappears after robbing Loren's store and leaving his sick baby with Dr. Mike.
When Sully is beaten and left for dead by skinners who are slaughtering buffalo, Dr. Mike fears he may be paralyzed.
After Gen. Custer injures Cloud Dancing and sentences him to hang, Dr. Mike and Sully orchestrate his escape.
A lonely Dr. Mike believes the whole town feels sorry for her as she prepares to celebrate another birthday as an unmarried woman.
Dr. Mike is at odds with Matthew when he announces his decision to forgo a university education and marry Ingrid.
Influenced by romance novels, Colleen develops a crush on Sully and endangers her life when she sets up a situation in which he must rescue her.
Dr. Mike is forced to operate on Brian after he suffers a severe head injury; the townspeople argue over the construction of a new school.
When one of Dr. Mike's patients dies and leaves behind an illegitimate child, Hank is forced to admit he is the boy's father.
When a famous Civil War photographer arrives to take a town portrait, he is delayed by bickering, and Dr. Mike discovers he is going blind.