When a person goes missing, the first 48 hours are the most crucial in an investigation.
A History of Violence
S2 E1
Police suspect that one man may be responsible for the disappearances of two women and their young children.
Desperate Measures; The Big City
S2 E2
A missing mother of four leaves behind a suicide note; a detective searches for a disoriented woman wandering the streets of Chicago.
Deleted; Cruel Streets
S2 E4
An online predator may be behind the disappearance of an aspiring model; police race to locate a mentally disabled man before he becomes a victim of street violence.
A woman reports her husband missing the day after their second wedding anniversary; a missing hotel guest is spotted on surveillance video leaving the establishment.
Police detectives investigate the subculture of Chicago's black gay males when a young man leaves a disturbing voice mail message and then goes missing.
3:10 to Yuma; Harm's Way
S2 E7
A man reports that his missing girlfriend left him an ominous phone call; a Chicago teenager falls under the influence of a gang member considered to be armed and dangerous.
Detectives search for an elderly woman who vanished after returning from a doctor's appointment, with the suspicion that the use of pain medication may have contributed to her disappearance.
Critical Care
S1 E2
Caretaker reports her 63-year-old cancer patient is missing; a missing mattress may solve the case.
Detectives search for a 14-year-old girl who was snatched by an older teen with possible gang connections; an elderly man with serious neurological problems goes missing.
Worried Sick; Silent Night
S1 E5
A 17-year-old teen and her child are missing; an elderly man vanishes en route to a Christmas party.