Natalie and her bedridden mother, Felicia, have been plagued with obesity for most of their lives; Dr. Procter vows to give them both weight loss surgery if Natalie can lose weight and Felicia can walk again.
After years trying to pray the gay away, Ty confronts his relationship with the church in order to lose weight and let his inner drag queen shine.
Years of neglect and criticism from her two sisters led Molly to pack on the pounds; now she must repair her relationship with family and food in order to get bariatric surgery.
Niki's softball career is cut short by her obesity; she wants to relive her dreams by coaching her son, but her food addiction threatens her ability to live her dreams and get bariatric surgery.
Keith's big size is on the verge of ruining his marriage and his health; he must fight the temptations of a cruise vacation in order to make weight for life-saving bariatric surgery.
Crystal has been hiding her sexuality from her family and close friends for years; that secret has fueled an eating addiction, and Crystal needs bariatric surgery to save her life.
Bryan's obesity has caused him to be depressed and miss too many activities with his friends; on top of that, he is desperate to spend more time with his daughter; Bryan decides bariatric surgery is the only way to transform his body and his life.
Meghan hopes to get weight loss surgery along with her overweight best friend, Vannessa; Vannessa is afraid of trying to lose weight only to fail; when Vannessa sees Meghan successfully lose weight, she changes her mind.
Corey is a young gay man who is just getting back on his feet after being homeless; he has dreams of getting back into college and finding a serious relationship, but he needs to make changes if he is going to live his dreams.
After Dr. Procter postpones Corey's bariatric surgery and increases his weight loss target, Corey tries to stay focused; a successful blind date provides a welcome boost of confidence before Corey's impending surgery approval.