A member of the Chicago Police Department launches the Women's DNA Initiative to fund the testing of rape kits; a deputy district attorney in Sacramento County, Calif., uses a DNA grant to find a killer.
Police in Albany, N.Y., get a surprise when a killer they think targets only older women is suspected in the murder of an elderly man; the contents of a secret storage shed hold the clues to a murder that has gone cold for more than 14 years.
Young girls are sexually assaulted while waiting for their school buses; in 1991, a 9-year-old girl disappears from her home and is found murdered.
A brother is a suspect in the case of a 12-year-old found dead in her home in 1998; a 69-year-old woman is the victim of rape and murder in 1984.
In 1995, two women are raped in Louisville, Ky.; in 1982, a young man is found murdered in Deadwood, S.D.
Detective Danny Reyes investigates the 1990 murder of a Fort Worth, Texas woman.
Police go under cover to catch a man they suspect of killing three prostitutes; a letter opener links a priest to the murder of a nun.
A banker is beaten to death in his bed; a man with a guilty conscience helps police.
After U.S. Navy sailor disappears in 68, the Navy claims he went AWOL; but his sister works for over 30 years to prove that he was really killed; DNA from a cigarette butt helps detectives to unravel a 20-year-old case of rape and murder.
A 25-year-old woman is killed in a hotel room in 1978; a 25-year-old woman is shot to death during a jewelry-store robbery in 1980.
Guns found dumped in a pond help police to solve the 15-year-old murder of Detroit cab company owner; the rape and murder of an Atlanta TV station receptionist goes cold for 20 years before DNA links a man to the crime.
Fingerprints lifted from two beer bottles help a California detective track down a prostitute's killer; the investigations of a woman's murder and the death of a man killed in a car crash use DNA analysis.
Nearly 20 years after they first suspect him, police arrest Gary Ridgway, the most prolific known serial killer in U.S. history.
BTK Dennis Rader terrorizes Wichita, Kan., for decades, leaving at least 10 murder victims in his wake.
A wild hunch pays off in the capture of a serial rapist; investigators solve the murder of a 6-year-old girl; a man gives police the information they need to solve a case; a murder baffles Indiana police.
A detective tracks down a man who raped and murdered a 6-year-old girl 10 years earlier; police search for the killer of an 18-year-old hitchhiker.
A cell phone and an ATM card lead to the apprehension of a rapist.
Det. Vince Velazquez of Atlanta and Capt. Russell Popham of East Point, Ga., work to solve the 1995 rape and murder of 14-year-old Nacole Smith, one of Atlanta's most notorious unsolved crimes.
DNA evidence solves the murder of a female law student; a man confesses to the random killing of a bowhunter.
A wiretapped conversation between a suspected killer and his sister cracks a 9-year-old murder case; a geologist finds human bones, solving the murder of a Virginia woman.
A phone-sting operation helps police to nab killers; a district attorney uses a "John Doe"' warrant in the hunt for a rapist.
Business cards found at the scene reveal the killer of a New York teen; a murder suspect confesses after police take DNA samples from him.
Forensic testing helps to solve the murder of a beauty queen; two hairs help to put a double-murderer behind bars.
An ex-girlfriend helps to bring a child-murderer to justice; a mysterious set of bones puts police on the trail of a teen's killer.
A man is convicted in the gruesome murders of four black female prostitutes in Miami; detectives nail the rapist-killer of a 6-year-old girl.
DNA on a scarf helps to convict a homeless man of murder; a victim's phone call and his own writings help to convict a man who imprisoned teens in an underground bunker.
DNA evidence helps to convict the man who raped and killed an elderly woman; shell casings help to convict the killer of a security guard.
Fifteen years after a husband is convicted of murder, police discover that he may have been wrongly accused.
The infant subject of a child-custody dispute is found burned; a body is discovered in a home's crawlspace.
Bite marks help to get a child predator off the streets; after a decade, justice is finally served in the slaying of a 15-year-old girl.
Police hunt for over 15 years for a serial killer who lures women to Kansas for sadomasochistic sexual trysts at hotels; unprecedented access to surveillance photos and video from the investigation provides a glimpse inside the probe.
Detectives suspect that several violent crimes are connected; a maintenance man finds a body in a bathroom.
A 51-year-old man is shot to death near his horse stable; a rapist is sentenced to more than 1,000 years in prison.
The body of a man killed by a bullet is found in his well; detectives try to connect a man to his ex-wife's murder.
Detectives search for a man who rapes and kills women; an ex-girlfriend is the prime suspect when a man goes missing.
DNA evidence leads to the arrest of Houston's notorious "tourniquet killer"; a young woman is found shot and burned in an olive orchard.
James Allen Selby, a serial rapist who eluded police for years.
A detective vows not to shave until he solves the murder of a young woman; investigators track down a killer with the help of DNA found on duct tape used on the victim.
An unresolved murder from 1974 leads back to a high school janitor; a man confesses to killing his girlfriend.
A man gives police the information they need to solve a case; a murder baffles Indiana police.
A co-worker goes to check on a woman who failed to show up for work; a woman reports being raped in her home.
After a woman's disappearance, the Los Angeles police get an anonymous call to investigate a suspect; an eyelash is a clue in the death of a woman stabbed many times.
After 46 years, homicide detectives take a lovers-lane bandit into custody; a suspected killer has an identical twin.
The Zodiac killer provokes the police by sending clues to the media.
An undercover agent solves a 15-year-old crime; a former state trooper becomes the prime suspect in his wife's death.
A wife goes missing; a gas-station attendant is shot.
A suspected killer and identity thief bears a unique tattoo.
Forensic DNA analysts help to break the case of a man who killed 49 women.
Advances in DNA technology help to convict a teen's murderer nearly 30 years after his crime; hair evidence helps to put a child's killer in prison.
Saliva seals a killer's doom; DNA from the victim's son solves a murder; an arson investigator is accused of setting fires; a neighbor rapes, robs and murders an older woman.
Testimony about the growth of larvae in dead bodies helps to convict a family's killer; the 2001 murder of a young girl remains unsolved.
A cold case is solved when the killer's attempt to murder another woman goes awry; an intrepid reporter helps to crack a case previously thought to be an accident.
Forensic DNA analysts help to break the case of a man who killed 49 prostitutes and other women; a forensic anthropologist painstakingly pieces 97 bone fragments back together to solve a woman's murder.
A suspected killer and identity thief bears a unique tattoo; toxicology solves a woman's murder; a sheriff tries to get a woman to confess to killing her two babies.
DNA technology solves two stabbing cases; an anonymous call leads to a child's killer.
Testimony about the growth of larvae in dead bodies helps to convict a family's killer; the 2001 murder of a young girl; a New Orleans police officer goes under cover on a riverboat; a man goes on trial for a murder 10 years earlier.
A man suspected of the cold case murder of his wife and son hatches a new plot to kill his mother and father; detectives solve the 20-year-old murder of a teenager by tricking her killer into licking an envelope.
A dry cleaning tag inside a sweatshirt left at a crime scene helps police track down a serial killer and rapist who had been eluding them for years.
Prostitute helps police to track down a serial killer; elaborate sting; detectives from three departments hunt a serial killer; woman is found murdered under a hotel bed.
A wild hunch pays off in the capture of a serial rapist; investigators solve the murder of a 6-year-old girl.
DNA technology solves two stabbing cases; an anonymous call leads to a child's killer; a 3-year-old boy provides police with evidence in a murder case; a murdered housewife is buried in her own cellar.
A New Orleans police officer goes under cover on a riverboat; a Wisconsin man goes on trial for a murder 10 years earlier.
Bite marks lead to a murder conviction; a young woman is found dead in her bathtub; discovery of a human scalp helps convict a murderer; teen kidnaps and kills younger boys.
A forensic anthropologist becomes an expert on the human body's rate of decay.
A woman helps to solve her mother's murder; an officer solves the murder of a newspaper-delivery woman.
A killer helps convict himself when he boasts about his crime to his prison cellmates; a pregnant woman is found dead.
DNA evidence on cigarettes; confession to a TV star; re-enactment; divers.
A re-enactment of a toddler's death is responsible for solving the crime; divers manage to locate a body.
After receiving a crucial clue, police solve a woman's murder more than 20 years after the fact.
A boy's toy car provides an important clue for detectives as they struggle to make a case against a serial killer.
A murder victim's niece starts an advocate group; a car preserves a victim's body.
DNA on a cigarette brings a rapist and murderer to justice; a confession made to a TV star helps police to solve a murder.
A respected Florida man's wife dies suddenly; the horrifying discovery of the remains of two newborn babies.
A fire investigator helps crack the case of an arsonist and killer; a prison inmate gives information about a murder that took place 15 years earlier.
A tool mark solves a murder; a disgruntled wife tells police that her husband is a killer.
The national DNA databank helps police hunt down a rapist; the re-enactment of a shooting death proves it was not an accident.
Investigators receive help from the internet when looking for a serial killer; a drug trafficker jumps bail.
A teenager leads police to the killer of three girls; a woman disappears from her sister's home.
Police suspect a former officer; a blow to the head of a garbage collector leaves strange markings; DNA may help to track down a stabber.
Police link four murders to a single DNA profile.
DNA connects two Michigan murders a decade apart; a single foreign hair helps police to find a killer.
A woman is suspected of murdering two of her daughters when a third convinces police to reopen the cases.
A 3-year-old boy provides police with evidence in a murder case; a murdered housewife is buried in her own cellar.
Englishwoman shot; fingerprint matches prisoner; DNA databank helps catch stalker.
A Missouri woman is convicted of killing her stepdaughter; a skeleton leads police to a serial killer.
Alligators help to solve a murder investigation; Phoenix police solve a 20-year-old homicide.
A Florida man vanishes; crash victim is found to have been shot.
A woman kills her husband in a satanic rite; a woman tracks down the man who raped her.
Forensic clay modeling helps investigators identify a murder victim; two boys perform satanic rituals and set fires.
Woman's body hidden in a refrigerator; murder of a deputy sheriff.
Divers find a skeleton in a car at the bottom of a river; a dead dog's DNA helps to crack open a case.
Discovery of a human scalp helps convict a murderer; teen kidnaps, tortures and kills younger boys.
A serial killer keeps law enforcement working on his cases for over 20 years.
A forensic anthropologist painstakingly pieces 97 bone fragments back together to solve a woman's murder.
Police thaw a frozen body with a hair dryer and solve the case; when a child's body is found in a Chicago garden, authorities track down a strange family.